Our solar system is moving at approx. 52,000 mph, so where is the Alpha Centauri system, which is assumed to be also moving through interstellar space at a similar velocity since it is part of our Galaxy. Is the A. Centauri system moving in front of us at 12 o’clock, parallel to us at 3 o’clock, or some other configuration?
If you were looking down on the galaxy from above with 12 o'clock pointing from the Sun to the Galactic center, then using SIMBAD we can get the galactic co-ordinates as approx (315,-0.6) in longitude, latitude respectively. Longitude is measured anti-clockwise from the line from the Sun to the galactic center, so Alpha Cen would be approximately between 1 and 2 o'clock. ESO have a map here showing the nearby stars within 12.5 light years.
So if I have this correct: Alpha Centauri is at 1:30 pm (315 degrees), where noon is a line from the sun to galactic center, and our galactic rotation is to the left (toward 9 o’clock, or 90 degrees off of center, clockwise when viewed from above the Galactic North Pole) - then Alpha Centauri is fractionally closer to the center, and trailing us slightly in terms of galactic rotation.